Enthesitis related arthritis- 2 distinct clinical phenotypes?

نویسندگان

  • Corinne Fisher
  • John Ioannou
  • Debajit Sen
چکیده

Background Enthesitis related arthritis (ERA) is the subtype of juvenile idiopathic arthritis (JIA) as defined by the International League of Associations for Rheumatology (ILAR) classification (2004). Asymmetrical lower limb arthritis and enthesitis are said to be prominent early features with axial inflammation a late feature. In our cohort of patients with ERA we observed this was often not the casewith axial inflammation occurring early and the emergence of 2 distinct clinical phenotypes.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Enthesitis Related Arthritis; a New Era of Understanding

Enthesitis related arthritis (ERA) is one of the most poorly understood and under-researched forms of childhood arthritis. Emerging evidence suggests that inflammatory spinal arthritis occurs earlier than previously thought and that there may be 2 distinct clinical phenotypes of diseasethose with predominantly axial ERA and those with peripheral arthritis and enthesitis, who never develop spina...

متن کامل

Nutritional supplementation and dietary restriction in the resolution of enthesitis-related arthritis

Previously considered a chronic condition, enthesitis-related arthritis – a type of juvenile idiopathic arthritis – may in some cases represent a sensitivity-related illness and thus respond to antigenic avoidance and remediation of biochemistry. Enthesitis-related arthritis is a rare but serious cause of childhood disability and chronic pain that often leads to continuing complications in adul...

متن کامل

Diagnosis and treatment of enthesitis-related arthritis

Juvenile idiopathic arthritis (JIA) is a chronic, inflammatory disease of unknown etiology. The enthesitis-related arthritis (ERA) JIA category describes a clinically heterogeneous group of children including some who have predominately enthesitis, enthesitis and arthritis, juvenile ankylosing spondylitis, or inflammatory bowel disease-associated arthropathy. ERA accounts for 10%-20% of JIA. Co...

متن کامل

Enthesitis-related arthritis: time to re-define?

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in childhood. Enthesitis-related arthritis (ERA) is one of the seven JIA subtypes classified by the International League of Associations for Rheumatology (ILAR). Due to inclusion and exclusion criteria, a pitfall of the ERA category is that it does not include all subsets of juvenile spondyloarthropathy, with many children...

متن کامل

Anti-cyclic citrullinated peptide: its prevalence and clinical significance in a South African cohort with juvenile idiopathic arthritis

Results Records of 52 patients (54% males, 46% females) were reviewed. The mean (SD) age and follow-up period were 10.69 (3.81) and 2.3 (1.7) years, respectively. The majority of the children (83%) were Black. The subtypes of JIA were as follows: systemic 21%, polyarticular 50%, oligoarticular 19%, enthesitis-related arthritis 2%, psoriatic 2% and other 6%. Anti-CCP antibodies were present in t...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2011